Next's new store at Bedford s Interchange Retail Park will be unveiled on Monday morning (April 12).
As well as womenswear, menswear, kidswear and a home department, the relocation will include Mamas & Papas and Ground Coffee concessions.
The 38,058 sq ft store an extra will open Monday to Friday 8.30am to 8.30pm, Saturday from 8.30am to 7pm and Sunday, between 11am to 5pm.
A spokesman for Next confirmed the relocation has no correlation to the town centre store.
Andrea Lane, store manager, said: "The team and I are greatly looking forward to welcoming our customers to the long-awaited new store that has grown significantly and now boasts an amazing home department.
"We know our customers are going to love spending time in the Ground Coffee shop and browsing in our Mamas & Papas concession, so, whether it's in store shopping or online orders, we look forward to see you."