Former Blues Mouritz Botha (Saracens) and Billy Twelvetrees (Gloucester Rugby) were among the 10 players released by England ahead of Saturday’s QBE International against Fiji at Twickenham Stadium.
Ex-Blues Dan Cole (Leicester Tigers) and Tom Youngs (Leicester Tigers) remain in the squad for the fixture.
England Head Coach Stuart Lancaster said: “We have had a good two days back at Pennyhill Park and the players have been very focused on delivering against Fiji.
“Saturday is a great opportunity for us to put a marker down and deliver a quality performance. It’s great to have young players such as Mako Vunipola and Joe Launchbury get their opportunities in the match-day 23 and we are excited about the potential of the squad.
“Under the agreement with Premiership Rugby we are releasing some players back, including Alex Corbisiero, will play for London Irish and we are looking forward to seeing how he goes.”